|
1849
|
Record
of 1 case each of haemoptysis, phthisis, scrofula.
|
|
1900
|
845
deaths from TB, equivalent to 200 per 100,000.
|
|
1939
|
- Before
the invasion by Japan, statistical figures showed
that 4,443 died from TB, equivalent to 250 per
100,000
-
TB became a notifiable disease
|
|
1939
- 1945
|
During
the wars, TB was a major killer disease due to
a number of factors: unstable social conditions,
poor nutrition, and serious overcrowding.
|
|
After
the war
|
TB
was the top cause of death. The influx of
refugees from Mainland China into Hong Kong further
aggravated the situation.
|
|
1940-1950
|
There
was great development in anti-TB drugs. The Hong
Kong Government liaised with The Hong Kong Anti-Tuberculosis
Association to develop plans for TB control services.
|
|
1949
|
The
Hong Kong Anti-Tuberculosis Association built
the Ruttonjee Sanatorium in the site of the previous
Navy Hospital, to provide services for TB patients.
|
|
1951
|
Streptomycin
was used for treatment of TB.
|
|
1952
|
BCG
vaccination was given to newborn babies and school
children.
|
|
1950-60's
|
It
was noted that about 3 quarters of the TB patients
did not complete the whole course of anti-TB treatment.
Hence, the use of supervised treatment (later
known as DOT, directly observed treatment) was
considered.
|
|
1962
|
Anti-TB
treatment regimens were used, including the use
of daily streptomycin (injection), para-aminosalicylic
acid, and isoniazid, followed by monthly supply
of PASINAH (para-aminosalicylic acid, and isoniazid)
tablets, for a total duration of 18 to 24 months.
|
|
1964
|
The
number of TB cases and death cases were 12,557
and 1,441 respectively.
|
|
1967
|
The
Government Chest Service formally liaised with
the British Medical Research Council in various
research projects.
|
|
1970
|
Fully
supervised treatment (DOT) was used on a service
basis. The number of new cases and deaths decreased
to 10,077 and 1,436 respectively.Since then, TB
gradually became under control and the figures
dropped gradually.
|
|
1979
|
Short
course service programme (6 months) was implemented
for treating TB patients.
|
|
1995
|
The
number of new cases of TB was 6,212.
|
|
1996-2000
|
There
has been an apparent trend of a slight rise in
the number of TB cases. Each year there were about
7,000 cases.
|
|
2001
|
TB
rate dropped to 108.0 per 100,000.
|
|
2002
|
TB
rate dropped to 97.3 per 100,000 ( below 100 for
the first time).
|
|
2004
|
In some cases of multidrug-resistant tuberculosis (MDR-TB) which
were extraordinarily difficult to treat, linezolid was used as
part of the early-stage treatment regimen to enhance efficacy
of the treatment.
|
|
2006
|
Extensively drug-resistant TB (XDR-TB) was defined as a
relatively important type of MDR-TB.
|
|
2008
|
The Prevention and Control of Disease Ordinance took effect and
became a new legislation to strengthen the control of
communicable diseases, including TB.
|
|
2009
|
Dosage of linezolid was optimised for use in longer treatment
periods so that the success rates of the treatment of MDR-TB
might be increased.
|
|
2011
|
The number of TB notifications dropped below the ratio of 70
cases per 100 000 population for the first time.
|
|
2014
|
Delamanid, a new anti-TB drug, was introduced to strengthen the
treatment of MDR-TB.
|
|
2016
|
The number of TB notifications dropped below the ratio of 60 cases per 100 000 population for the first time.
|
|
2017
|
Bedaquiline, a new anti-TB drug, was introduced to strengthen the treatment of MDR-TB.
|
